| Item type |
文献 / Documents(1) |
| 公開日 |
2024-04-16 |
| アクセス権 |
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アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_db06 |
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資源タイプ |
doctoral thesis |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.1016/j.nut.2023.112184 |
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関連名称 |
10.1016/j.nut.2023.112184 |
| 出版タイプ |
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出版タイプ |
NA |
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出版タイプResource |
http://purl.org/coar/version/c_be7fb7dd8ff6fe43 |
| タイトル |
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タイトル |
Development and validation of equations for predicting appendicular skeletal muscle mass in male patients with head and neck cancer and normal hydration status |
| タイトル別表記 |
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その他のタイトル |
正常な体水分状態の男性の頭頸部がん患者における四肢骨格筋量を予測する回帰式の妥当性検証 |
| 著者 |
久保, みゆ
(安井)山田, 苑子
ハヤシ, ハルカ
キタオ, ミドリ
ワダ, キョウコ
ヤマナカ, アヤカ
オオマエ, ナオ
マツオカ, モモヨ
神村, 盛一郎
島田, 亜紀
北村, 嘉章
濵田, 康弘
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| 抄録 |
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内容記述 |
Muscle mass is typically assessed by abdominal computed tomography, magnetic resonance imaging, and dual-energy x-ray absorptiometry. However, these tests are not routinely performed in patients with head and neck cancer (HNC), making sarcopenia assessment difficult. The aim of this study was to develop and validate equations for predicting appendicular skeletal muscle mass (ASM) from data obtained in daily medical practice, with bioelectrical impedance analysis (BIA)-measured appendicular skeletal muscle mass (BIA-ASM) as a reference.
Methods: This cross-sectional study included 103 men with HNC who were randomly placed into development and validation groups. The prediction equations for BIA-ASM were developed by multiple regression analysis and validated by Bland–Altman analyses. The estimated skeletal muscle mass index (eSMI) was also statistically evaluated to discriminate the cutoff value for BIA-measured SMI according to the Asian Working Groups for Sarcopenia.
Results: Two practical equations, which included 24-h urinary creatinine excretion volume (24hUCrV), handgrip strength (HGS), body weight (BW), and body height (BHt), were developed: ASM (kg) = –39.46 + (3.557 x 24hUCrV [g]) + (0.08872 x HGS [kg]) + (0.1263 x BW [kg]) + (0.2661 x BHt [cm]) if available for 24hUCrV (adjusted R2 = 0.8905), and ASM (kg) = –42.60 + (0.1643 x HGS [kg]) + (0.1589 x BW [kg]) + (0.2807 x BHt [cm]) if not (adjusted R2 = 0.8589). ASM estimated by these two equations showed a significantly strong correlation with BIA-ASM (R > 0.900). Bland–Altman analyses showed a good agreement, and eSMI accuracy was high (>80%) in both equations.
Conclusions: These two equations are a valid option for estimating ASM and diagnosing sarcopenia in patients with HNC in all facilities without special equipment. |
| キーワード |
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|
主題 |
Appendicular skeletal muscle mass |
| キーワード |
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主題 |
Bioelectrical impedance analysis |
| キーワード |
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主題 |
Estimation equation |
| キーワード |
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|
主題 |
Head and neck cancer |
| キーワード |
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主題 |
Sarcopenia |
| キーワード |
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主題 |
Skeletal muscle mass index |
| 書誌情報 |
en : Nutrition
巻 116,
p. 112184,
発行日 2023-08-06
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| 収録物ID |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
08999007 |
| 収録物ID |
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
18731244 |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA10745727 |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11535297 |
| 出版者 |
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出版者 |
Elsevier |
| 備考 |
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値 |
内容要旨・審査要旨・論文本文の公開
本論文は，著者Miyu Kuboの学位論文として提出され，学位審査・授与の対象となっている。
学位授与者所属 : 徳島大学大学院医科栄養学研究科（医科栄養学専攻） |
| EID |
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識別子 |
405948 |
| 言語 |
|
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言語 |
eng |
| 報告番号 |
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学位授与番号 |
甲第3868号 |
| 学位記番号 |
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|
値 |
甲栄第312号 |
| 学位授与年月日 |
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学位授与年月日 |
2025-03-13 |
| 学位名 |
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学位名 |
博士（栄養学） |
| 学位授与機関 |
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学位授与機関名 |
徳島大学 |
k3868_abstract.pdf (103 KB)
