| Item type |
文献 / Documents(1) |
| 公開日 |
2024-04-30 |
| アクセス権 |
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アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.2176/nmc.oa.2018-0203 |
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言語 |
ja |
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|
関連名称 |
10.2176/nmc.oa.2018-0203 |
| 出版タイプ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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|
タイトル |
Ex Vivo Assessment of Various Histological Differentiation in Human Carotid Plaque with Near-infrared Spectroscopy Using Multiple Wavelengths |
|
言語 |
en |
| タイトル別表記 |
|
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その他のタイトル |
Assessment of Carotid Plaque with Near-infrared Spectroscopy |
|
言語 |
en |
| 著者 |
ムネミツ, トシヒロ
イシイ, アキラ
オカダ, エイジ
チハラ, ヒデオ
ヨシダ, カズミチ
タカハシ, ジュン
高木, 康志
ミヤモト, ススム
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
We previously reported that near-infrared hyperspectral imaging enabled the localization of atherosclerotic plaques from outside the vessels, but not the optical characteristics of each histological component. Therefore, the near-infrared spectrum of each component was collected from the sliced section of the human carotid plaque obtained with endarterectomy and the optical characteristics were confirmed in several wavelengths. Based on this information, we assessed the diagnostic accuracy for ex vivo chemogram in each plaque component created with near-infrared spectroscopy (NIRS), using multiple wavelengths. The chemogram projected on the actual image of plaque was created based on light intensity and transmittance change at three wavelengths. The wavelengths that were mainly were 1440, 1620, 1730, and 1930 nm. We evaluated the accuracy of histological diagnosis in chemogram compared with pathological findings, analyzing interobserver agreement with k-statistics. The chemograms that we created depicted the components of fibrous tissue, smooth muscle, lipid tissue, intraplaque hemorrhage, and calcification. Diagnostic odds ratio in each component was as follows: 259.6 in fibrous tissue, 144 in smooth muscle, 1123.5 in lipid tissue, 29.3 in intraplaque hemorrhage, and 136.3 in calcification. The k-statistics revealed that four components, excluding intraplaque hemorrhage, had substantial or almost perfect agreement. Thus, this study demonstrated the feasibility of using chemogram focused on specific component during the histological assessment of atherosclerotic plaques, highlighting its potential diagnostic ability. Chemograms of various target components can be created by combining multiple wavelengths. This technology may prove to be useful in improving the histological assessment of plaque using NIRS. |
|
言語 |
en |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
atherosclerosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
carotid plaque |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
carotid artery stenosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
near infrared spectroscopy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
plaque imaging |
| 書誌情報 |
en : Neurologia Medico-Chirurgica
巻 59,
号 5,
p. 163-171,
発行日 2019
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| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
04708105 |
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13498029 |
| 収録物ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00358613 |
| 出版者 |
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出版者 |
The Japan Neurosurgical Society |
|
言語 |
en |
| 権利情報 |
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|
言語 |
en |
|
権利情報 |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives International License. |
| EID |
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|
識別子 |
365932 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
nmc_59_5_163.pdf (1.98 MB)
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