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Mechanism and clinical use of botulinum neurotoxin in head and facial region
https://tokushima-u.repo.nii.ac.jp/records/2012101
https://tokushima-u.repo.nii.ac.jp/records/2012101682e5a45-70b0-42bd-a7a8-71eefa7957a3
| 名前 / ファイル | ライセンス | アクション |
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jpor_67_4_493.pdf (1.67 MB)
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| Item type | 文献 / Documents(1) | |||||||||||||||||||||||||
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| 公開日 | 2024-07-12 | |||||||||||||||||||||||||
| アクセス権 | ||||||||||||||||||||||||||
| アクセス権 | open access | |||||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||
| 出版社版DOI | ||||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||||
| 関連識別子 | https://doi.org/10.2186/jpr.JPR_D_22_00238 | |||||||||||||||||||||||||
| 言語 | ja | |||||||||||||||||||||||||
| 関連名称 | 10.2186/jpr.JPR_D_22_00238 | |||||||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||||
| タイトル | Mechanism and clinical use of botulinum neurotoxin in head and facial region | |||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 著者 |
Raman, Swarnalakshmi
× Raman, Swarnalakshmi
× ヤマモト, ユミコ
× 鈴木, 善貴
WEKO
706
× 松香, 芳三
WEKO
589
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| 抄録 | ||||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||||
| 内容記述 | Purpose: Botulinum neurotoxin (BoNT) is a biological toxin produced by Clostridium botulinum. BoNT is a potent toxin extensively used in therapeutic interventions. This review provides an updated overview of the mechanisms of action and clinical applications of BoNT in head and facial region. Study selection: MEDLINE/PubMed searches were conducted using the terms “botulinum neurotoxin” and “dentistry” along with a combination of other related terms. In addition, studies were manually selected from reference lists of the selected articles. Results: The Food and Drug Administration in the United States initially approved BoNT to treat strabismus, blepharospasm, and hemifacial spasms. The use of BoNT in dermatology and cosmetics has been widely established and has created a revolution in these fields. Over the years, its applications in various medical specialties have expanded widely. Owing to its safety, efficacy, and long duration of action, it is well-accepted by patients. BoNT/A and BoNT/B are widely used in clinical practice. Several off-label uses of BoNT in the dental fraternity have yielded promising results. We have elaborated on the speculated mechanism of action, dosage, effective sites of injection, and adverse effects of each therapeutic application. The various clinical indications for BoNT include bruxism, myofascial pain, temporomandibular joint dislocation, hemifacial pain, orofacial dystonia, facial paralysis, chronic migraine, and trigeminal neuralgia. Conclusions: BoNT is a safe treatment that can be used effectively, provided that the clinician has adequate knowledge regarding the mechanism, injection techniques, and local and systemic side effects and that it is administered cautiously and purposefully. |
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| 言語 | en | |||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||||
| 主題 | Botulinum neurotoxin | |||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||||
| 主題 | Clinical use | |||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||||
| 主題 | Orofacial | |||||||||||||||||||||||||
| キーワード | ||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||||||
| 主題 | Clostridium botulinum | |||||||||||||||||||||||||
| 書誌情報 |
en : Journal of Prosthodontic Research 巻 67, 号 4, p. 493-505, 発行日 2023-02-04 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||
| 収録物識別子 | 18839207 | |||||||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||
| 収録物識別子 | 18831958 | |||||||||||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||||||||||
| 収録物識別子 | AA12395171 | |||||||||||||||||||||||||
| 出版者 | ||||||||||||||||||||||||||
| 出版者 | Japan Prosthodontic Society | |||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 権利情報 | ||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||
| 権利情報 | This is an open-access article distributed under the terms of Creative Commons Attribution-NonCommercial License 4.0 (CC BY-NC 4.0), which allows users to distribute and copy the material in any format as long as credit is given to the Japan Prosthodontic Society. It should be noted however, that the material cannot be used for commercial purposes. | |||||||||||||||||||||||||
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| 識別子 | 393367 | |||||||||||||||||||||||||
| 識別子タイプ | URI | |||||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||||
