| Item type |
文献 / Documents(1) |
| 公開日 |
2025-02-26 |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1016/j.ejmp.2024.104850 |
|
|
関連名称 |
10.1016/j.ejmp.2024.104850 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Validation of Light–Ion Quantum Molecular Dynamics (LIQMD) model for hadron therapy |
| 著者 |
Sato, Yoshi-hide
Sakata, Dousatsu
Bolst, David
Simpson, Edward C.
Chacon, Andrew
Safavi-Naeini, Mitra
Guatelli, Susanna
芳賀, 昭弘
|
| 抄録 |
|
|
内容記述 |
Purpose: This study aims to validate the Light-Ion Quantum Molecular Dynamics (LIQMD) model, an advanced version of the QMD model for more accurate simulations in hadron therapy, incorporated into Geant4 (release 11.2).
Methods: Two sets of experiments are employed. The first includes positron-emitter distributions along the beam path for 350 MeV/u 12C ions incident on a PMMA target, obtained from in–vivo Positron Emission Tomography (PET) experiments at QST (Chiba, Japan). The second comprises cross-sections for 95 MeV/u 12C ions incident on thin targets (H, C, O, Al, and Ti), obtained from experiments at GANIL (Caen, France). The LIQMD model’s performance is compared with the experimental data and the default QMD model results.
Results: The LIQMD model can predict the profile shape of positron-emitting radionuclide yields with better accuracy than the default QMD model, although some discrepancies remains. The consistency observed in the production of positron-emitting radionuclides aligns with the thin target cross-section analysis. The LIQMD model significantly improves the differential and double-differential cross-sections of fragments produced in thin targets, especially in the forward direction. The overestimation of 10C production in the in–vivo PET benchmark is consistent with the 95 MeV/u 12C cross-section test. Overall, the LIQMD model demonstrates better agreement with experimental measurements for nearly all fragment species compared to the QMD model.
Conclusions: The LIQMD model offers an improved description of the fragmentation process in hadron therapy. Future work should involve further validation against additional experimental measurements to confirm these findings. |
| キーワード |
|
|
主題 |
Quantum Molecular Dynamics |
| キーワード |
|
|
主題 |
Geant4 |
| キーワード |
|
|
主題 |
Fragmentation |
| キーワード |
|
|
主題 |
In-vivo Positron Emission Tomography |
| キーワード |
|
|
主題 |
Cross-section |
| 書誌情報 |
en : Physica Medica
巻 128,
p. 104850,
発行日 2024-11-28
|
| 収録物ID |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1724191X |
| 収録物ID |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
11201797 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12796015 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11064306 |
| 出版者 |
|
|
出版者 |
Elsevier |
| 権利情報 |
|
|
権利情報 |
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| EID |
|
|
識別子 |
415056 |
| 言語 |
|
|
言語 |
eng |
ejmp_128_104850.pdf (4.8 MB)
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