| Item type |
文献 / Documents(1) |
| 公開日 |
2025-03-21 |
| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
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|
関連識別子 |
https://pubs.acs.org/doi/10.1021/acsanm.4c01899 |
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関連名称 |
10.1021/acsanm.4c01899 |
| 出版タイプ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Nitrogen-Doped Graphene Quantum Dots Incorporated into MOF-Derived NiCo Layered Double Hydroxides for Nonenzymatic Lactate Detection in Noninvasive Biosensors |
| 著者 |
Chang, Ling-Yu
Rinawati, Mia
Guo, Yi-Ting
Lin, Yu-Chi
Chang, Chia-Yu
Su, Wei-Nien
水口, 仁志
Huang, Wei-Hsiang
Chen, Jeng-Lung
Yeh, Min-Hsin
|
| 抄録 |
|
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内容記述 |
Rapid interest in identifying specific biomarkers has been sparked by the development of wearable electrochemical sensors for physiological and biological monitoring via noninvasive measurement. During anaerobic metabolic circumstances, monitoring the lactate content become critical for noninvasive diagnostic of hypoxia. To improve the sensitivity of wearable sweat biosensors for detecting lactate concentrations, in this study, metal–organic framework (MOF)-derived NiCo-based layered double hydroxides (m-NiCo LDHs) with N-doped graphene quantum dots (NGQDs) decoration are designed. According to the X-ray absorption spectroscopy (XAS) analysis, the incorporation of NGQDs will alter the local electronic structure of transition metals in m-NiCo LDHs, thereby reducing the charge transfer resistance and accelerating the electron transfer kinetics during electrochemical reactions of lactate detection. After understanding the role of NGQDs in the matrix of m-NiCo LDHs, as-designed NGQD/m-NiCo LDH-based electrochemical biosensors for lactate detection displayed superior sensitivity of 62.63 ± 1.50 μA mM–1 cm–2 under an applied potential of 0.60 V (vs Ag/AgCl/3 M KCl) with the lactate concentration range of 0 to 15 mM in alkaline condition, compared to pristine NiCo LDH (16.77 ± 1.70 μA mM–1 cm–2)- and m-NiCo LDH (45.45 ± 4.39 μA mM–1 cm–2)-based ones. This research provides a potential electrocatalyst of GQD-modified MOF-derived LDHs for using enzyme-free electrochemical lactate sensors with reliable and stable performance in order to implement noninvasive human perspiration monitoring on wearable bioelectronics. |
| キーワード |
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|
主題 |
graphene quantum dots |
| キーワード |
|
|
主題 |
lactate |
| キーワード |
|
|
主題 |
layered double hydroxides |
| キーワード |
|
|
主題 |
metal−organic framework |
| キーワード |
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|
主題 |
enzyme-free |
| キーワード |
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|
主題 |
noninvasive |
| 書誌情報 |
en : ACS Applied Nano Materials
巻 7,
号 12,
p. 14431-14442,
発行日 2024-06-06
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| 収録物ID |
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
25740970 |
| 出版者 |
|
|
出版者 |
ACS Publications |
| 権利情報 |
|
|
権利情報 |
This article is licensed under CC-BY 4.0. |
| EID |
|
|
識別子 |
409284 |
| 言語 |
|
|
言語 |
eng |
acsanm_7_12_14431.pdf (8 MB)
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