| Item type |
文献 / Documents(1) |
| 公開日 |
2025-03-18 |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.3390/antibiotics11081120 |
|
|
関連名称 |
10.3390/antibiotics11081120 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Characteristics of Antibiotic Resistance and Tolerance of Environmentally Endemic Pseudomonas aeruginosa |
| 著者 |
Kim, Seryoung
Masai, Satomi
村上, 圭史
東, 桃代
片岡, 佳子
Sebe, Mayu
Shimizu, Kazuya
Itayama, Tomoaki
Whangchai, Niwooti
Whangchai, Kanda
Ihara, Ikko
間世田, 英明
|
| 抄録 |
|
|
内容記述 |
Antibiotic-resistant bacteria remain a serious public health threat. In order to determine the percentage of antibiotic-resistant and -tolerant Pseudomonas aeruginosa cells present and to provide a more detailed infection risk of bacteria present in the environment, an isolation method using a combination of 41 ◦C culture and specific primers was established to evaluate P. aeruginosa in the environment. The 50 strains were randomly selected among 110 isolated from the river. The results of antibiotic susceptibility evaluation showed that only 4% of environmental strains were classified as antibiotic-resistant, while 35.7% of clinical strains isolated in the same area were antibiotic-resistant, indicating a clear difference between environmental and clinical strains. However, the percentage of antibiotic-tolerance, an indicator of potential resistance risk for strains that have not become resistant, was 78.8% for clinical strains and 90% for environmental strains, suggesting that P. aeruginosa, a known cause of nosocomial infections, has a high rate of antibiotic-tolerance even in environmentally derived strains. It suggested that the rate of antibiotic-tolerance is not elicited by the presence or absence of antimicrobial exposure. The combination of established isolation and risk analysis methods presented in this study should provide accurate and efficient information on the risk level of P. aeruginosa in various regions and samples. |
| キーワード |
|
|
主題 |
Pseudomonas aeruginosa |
| キーワード |
|
|
主題 |
antibiotic-tolerance |
| キーワード |
|
|
主題 |
antibiotic-resistance |
| キーワード |
|
|
主題 |
environment |
| 書誌情報 |
en : Antibiotics
巻 11,
号 8,
p. 1120,
発行日 2022-08-18
|
| 収録物ID |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
20796382 |
| 出版者 |
|
|
出版者 |
MDPI |
| 権利情報 |
|
|
権利情報 |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| EID |
|
|
識別子 |
413897 |
| 言語 |
|
|
言語 |
eng |
anti_11_8_1120.pdf (3.5 MB)
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