| Item type |
文献 / Documents(1) |
| 公開日 |
2025-03-18 |
| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
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|
関連識別子 |
https://doi.org/10.3390/ceramics6040132 |
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関連名称 |
10.3390/ceramics6040132 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Preparation and Characterization of Freeze-Dried β-Tricalcium Phosphate/Barium Titanate/Collagen Composite Scaffolds for Bone Tissue Engineering in Orthopedic Applications |
| 著者 |
Putra, Dwi Fortuna Anjusa
Aji, Bramantyo Bayu
Ningsih, Henni Setia
Wu, Ting-Wei
Nakanishi, Akihiro
森賀, 俊広
Shih, Shao-Ju
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| 抄録 |
|
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内容記述 |
The freeze-drying method creates a scaffold with a composite mesoporous structure with many advantages. However, everyday materials such as β-tricalcium phosphate (β-TCP) have been used as an orthopedic implant for canine tribal bone defects for decades, for instance, for grafting material of even shapes to form an implant for our teeth. However, this material is still not entirely expected to be the best implant due to its high biodegradability. Besides that, using the piezoelectric effect on the bone can lead to more efficiency in cell growth and a faster healing time for patients. Based on this phenomenon, a scaffold composite with a piezoelectric material such as barium titanate (BaTiO3/BT) has been tested. Based on the BT/β-TCP ratio, the scaffold composite of BT and β-TCP produces a porous structure with porosity ranging from 30.25 ± 11.28 to 15.25 ± 11.28 μm. The BT/β-TCP ratio influences the samples’ pore type, which affects each sample’s mechanical properties. In our result, the scaffold of 45.0 wt% BT/45.0 wt% β-TCP/10.0 wt% collagen has achieved a significant value of 0.5 MPa for maximum stress with a sufficient pore size of 25.32 ± 8.05 μm. Finally, we performed a viability test to see the sample’s piezoelectric effect, which showed that the piezoelectric effect does increase bone healing time when tested by growing MC3T3-E1 cells on the samples. |
| キーワード |
|
|
主題 |
freeze-dried |
| キーワード |
|
|
主題 |
barium titanate |
| キーワード |
|
|
主題 |
β-tricalcium phosphate |
| キーワード |
|
|
主題 |
piezoelectric |
| 書誌情報 |
en : Ceramics
巻 6,
号 4,
p. 2148-2161,
発行日 2023-11-11
|
| 収録物ID |
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|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
25716131 |
| 出版者 |
|
|
出版者 |
MDPI |
| 権利情報 |
|
|
権利情報 |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| EID |
|
|
識別子 |
412607 |
| 言語 |
|
|
言語 |
eng |
ceramics_6_4_2148.pdf (9.4 MB)
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