| Item type |
文献 / Documents(1) |
| 公開日 |
2025-03-17 |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.3390/hygiene4010006 |
|
|
関連名称 |
10.3390/hygiene4010006 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Antimicrobial Efficacy of a Portable UV-C-Based Coating Activation Device against Candida albicans Biofilm and SARS-CoV-2 as an Additional Feature : An In Vitro Study |
| 著者 |
Putra Wigianto, Adityakrisna Yoshi
渡邉, 恵
岩脇, 有軌
後藤, 崇晴
Otsuki, Tamaki
市川, 哲雄
|
| 抄録 |
|
|
内容記述 |
This in vitro study aimed to confirm the effect of the additional features of Kirei Keep Light (KKL), a commercial UV-C irradiation system that was originally created for coating the surface of removable dentures with photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC), on the antimicrobial efficacy aspect against Candida albicans biofilm on a denture base material (PMMA) and SARS-CoV-2. Materials and Methods: The antimicrobial efficacy on C. albicans biofilm was evaluated through quantitative (CFU) and qualitative (SEM images) analysis of three groups: no treatment (control), KKL, and immersion in a disinfectant solution, MCAE. The quantitative evaluation on SARS-CoV-2 was performed by comparing the untreated (control) group and the KKL group. Results: In comparison with the control group (2.39 × 106 CFU/mL), KKL irradiation resulted in a 91.01% reduction in C. albicans biofilm (2.15 × 105 CFU/mL), whereas for the MCAE group, this reduction was 99.98% (4.64 × 102 CFU/mL). The SEM image results also corroborate the CFU results, which showed that the fewest clean surfaces were found in the control, and this gradually increased with KKL and MCAE. SARS-CoV-2 inhibition, indicated by its TCID50 value, demonstrated that KKL almost completely inhibited SARS-CoV-2 infection and replication (99.99% reduction). Conclusion: KKL possesses antimicrobial efficacy on C. albicans biofilm on PMMA and SARS-CoV-2. |
| キーワード |
|
|
主題 |
UV-C irradiation |
| キーワード |
|
|
主題 |
MPC coating |
| キーワード |
|
|
主題 |
Candida albicans |
| キーワード |
|
|
主題 |
SARS-CoV-2 |
| 書誌情報 |
en : Hygiene
巻 4,
号 1,
p. 93-102,
発行日 2024-02-18
|
| 収録物ID |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2673947X |
| 出版者 |
|
|
出版者 |
MDPI |
| 権利情報 |
|
|
権利情報 |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| EID |
|
|
識別子 |
405876 |
| 言語 |
|
|
言語 |
eng |
hygiene_4_1_93.pdf (19.6 MB)
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