| Item type |
文献 / Documents(1) |
| 公開日 |
2025-03-28 |
| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1055/a-2507-3829 |
|
|
関連名称 |
10.1055/a-2507-3829 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Development of a Novel Horner–Wadsworth–Emmons Reagent for the Facile Preparation of Mixed Phosphonoacetates |
| 著者 |
中尾, 允泰
Okamoto, Marie
Isetani, Satoshi
Imai, Ayato
北池, 秀次
佐野, 茂樹
|
| 抄録 |
|
|
内容記述 |
A novel Horner–Wadsworth–Emmons (HWE) reagent, methyl 2-[bis(3,4,5-trifluorophenoxy)phosphoryl]acetate, was synthesized by the reaction of methyl 2-(dichlorophosphoryl)acetate and 3,4,5-trifluorophenol. Sequential alcoholysis of this HWE reagent with isopropyl alcohol and benzyl alcohol on the phosphorus atom afforded the mixed phosphonoacetate, methyl 2-[(benzyloxy)(isopropoxy)phosphoryl]acetate, in 89% yield for the two steps. |
| キーワード |
|
|
主題 |
Horner–Wadsworth–Emmons reagents |
| キーワード |
|
|
主題 |
methyl 2-[bis(3,4,5-trifluorophenoxy)phosphoryl]acetate |
| キーワード |
|
|
主題 |
alcoholysis |
| キーワード |
|
|
主題 |
fluorophenols |
| キーワード |
|
|
主題 |
mixed phosphonoacetates |
| キーワード |
|
|
主題 |
phosphorus–sulfur bonds |
| キーワード |
|
|
主題 |
phosphonothioate |
| 書誌情報 |
en : SynOpen
巻 9,
号 1,
p. 131-137,
発行日 2025-03-05
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| 収録物ID |
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
25099396 |
| 出版者 |
|
|
出版者 |
Georg Thieme Verlag KG |
| 権利情報 |
|
|
権利情報 |
This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by/4.0/) |
| EID |
|
|
識別子 |
416885 |
| 言語 |
|
|
言語 |
eng |
syno_9_1_131.pdf (469 KB)
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