| Item type |
文献 / Documents(1) |
| 公開日 |
2017-11-22 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2152/jmi.51.20 |
|
|
言語 |
ja |
|
|
関連名称 |
10.2152/jmi.51.20 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Identification of possible protein machinery involved in the thermogenic function of brown adipose tissue |
|
言語 |
en |
| 著者 |
カジモト, カズアキ
山﨑, 尚志
片岡, 正俊
寺田, 弘
篠原, 康雄
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Brown adipose tissue (BAT) is believed to function by dissipating excess energy in mammals. It is very important to understand the energy metabolism held in BAT since disorder of its energy-dissipating function may cause obesity or lifestyle-related diseases such as hypertension and diabetes. This function in BAT is mainly attributable to uncoupling protein (UCP), specifically expressed in its mitochondria. This protein consumes excess energy as heat by dissipating the H+ gradient across the inner mitochondrial membrane that is utilized as a driving force for ATP synthesis. In this review article, in addition to providing a brief introduction to the functional properties of BAT and UCP, we also describe and discuss properties of cultured brown adipocytes and the results of our exploratory studies on protein components involved in the energy-dissipating function in BAT. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
brown adipose tissue |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
mitochondria |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
energy metabolism |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
uncoupling |
| 書誌情報 |
en : The journal of medical investigation : JMI
巻 51,
号 1-2,
p. 20-28,
発行日 2004-02
|
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13431420 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11166929 |
| EID |
|
|
識別子 |
84810 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
jmi_51_1-2_20.pdf (605 KB)
