| Item type |
文献 / Documents(1) |
| 公開日 |
2019-10-10 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
関連識別子 |
https://doi.org/10.1098/rstb.2019.0225 |
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|
関連名称 |
10.1098/rstb.2019.0225 |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| タイトル |
|
|
タイトル |
Regulatory mechanisms underlying the specification of the pupal-homologous stage in a hemimetabolous insect |
| タイトル別表記 |
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その他のタイトル |
Regulation of cricket metamorphosis |
| タイトル別表記 |
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その他のタイトル |
Respective roles of Kr-h1, Br and E93 in hemimetabolous metamorphosis |
| 著者 |
石丸, 善康
友成, さゆり
渡辺, 崇人
野地, 澄晴
三戸, 太郎
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| 抄録 |
|
|
内容記述 |
Juvenile hormones (JHs) and the genetic interaction between the transcription factors Krüppel homolog 1 (Kr-h1) and Broad (Br) regulate the transformation of insects from immature to adult forms in both types of metamorphosis (holometaboly with a pupal stage versus hemimetaboly with no pupal stage); however, knowledge about the exact instar in which this occurs is limited. Using the hemimetabolous cricket Gryllus bimaculatus (Gb), we demonstrate that a genetic interaction occurs among Gb’Kr-h1, Gb’Br and the adult-specifier transcription factor Gb’E93 from the sixth to final (eighth) nymphal instar. Gb’Kr-h1 and Gb’Br mRNAs were strongly expressed in the abdominal tissues of sixth instar nymphs, with precocious adult moults being induced by Gb’Kr-h1 or Gb’Br knockdown in the sixth instar. Depletion of Gb’Kr-h1 or Gb’Br up-regulates Gb’E93 in the sixth instar. In contrast, Gb’E93 knockdown at the sixth instar prevents nymphs transitioning to adults, instead producing supernumerary nymphs. Gb’E93 also represses Gb’Kr-h1 and Gb’Br expression in the penultimate nymphal instar, demonstrating its important role in adult differentiation. Our results suggest that the regulatory mechanisms underlying the pupal transition in holometabolous insects are evolutionarily conserved in hemimetabolous G. bimaculatus, with the penultimate and final nymphal periods being equivalent to the pupal stage. |
| キーワード |
|
|
主題 |
Gryllus bimaculatus |
| キーワード |
|
|
主題 |
insect metamorphosis |
| キーワード |
|
|
主題 |
Krüppel homolog 1 |
| キーワード |
|
|
主題 |
Broad complex |
| キーワード |
|
|
主題 |
E93 |
| 書誌情報 |
en : Philosophical Transactions of the Royal Society B : Biological Sciences
巻 374,
号 1783,
p. 20190225,
発行日 2019-08-26
|
| 収録物ID |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
09628436 |
| 収録物ID |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
14712970 |
| 収録物ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00772905 |
| 出版者 |
|
|
出版者 |
The Royal Society |
| EID |
|
|
識別子 |
359157 |
| 言語 |
|
|
言語 |
eng |
ptrsb_374_1783_20190225.pdf (1.99 MB)
