| アイテムタイプ |
文献 / Documents(1) |
| 公開日 |
2022-08-17 |
| アクセス権 |
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アクセス権 |
open access |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版社版DOI |
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関連識別子 |
https://doi.org/10.1167/iovs.62.3.27 |
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関連名称 |
10.1167/iovs.62.3.27 |
| 出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
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タイトル |
Changes in Choroidal Component Ratio and Circulation After Coffee Intake in Healthy Subjects |
| タイトル別表記 |
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その他のタイトル |
Choroidal Changes After Coffee Intake |
| 著者 |
ナガサト, ダイスケ
三田村, 佳典
江川, 麻理子
村尾, 史子
長澤, 利彦
コモリ, ナツミ
ソノダ, ショウゾウ
サカモト, タイジ
タブチ, ヒトシ
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| 抄録 |
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内容記述 |
PURPOSE. The effects of coffee intake on the ratio of stromal and luminal components in the choroid and the underlying mechanism remain unclear. This prospective cross-sectional study aimed to explore how coffee intake affects the choroidal component ratio and circulation.
METHODS. Forty-nine right eyes of healthy adult volunteers were evaluated as the coffee intake group. Thirty-two right eyes of healthy volunteers served as the control group. The participants consumed 185 mL of coffee or water, respectively, and the systemic hemodynamics, enhanced-depth imaging optical coherence tomographic (EDI-OCT) images, and foveal mean blur rate (MBR), an indicator of blood flow velocity, were recorded at baseline and after coffee or water intake. The EDI-OCT images were binarized using ImageJ software, and subfoveal choroidal thickness (SCT) and whole, luminal, and stromal choroidal areas were calculated.
RESULTS. In the coffee intake group, significant decreases in SCT and luminal area peaked at 60 minutes after intake (both P < 0.001), whereas a significant increase in MBR peaked at 30 minutes (P < 0.001). No significant stromal area fluctuations were observed. SCT and luminal area fluctuations exhibited a significant positive correlation (r = 0.978, P < 0.001). Significant negative correlations of luminal area fluctuations with MBR fluctuations were observed by stepwise regression analysis (r = –0.220, P < 0.001). The control group exhibited no significant fluctuations.
CONCLUSIONS. Coffee-induced choroidal thinning may result mainly from a reduction in the choroidal vessel lumen, and this vessel lumen reduction correlated with an increased choroidal blood flow velocity after coffee intake. These coffee-induced changes in choroidal component ratio and circulation should be considered when evaluating choroids. |
| キーワード |
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主題 |
choroidal structure |
| キーワード |
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主題 |
choroidal circulation |
| キーワード |
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主題 |
coffee |
| 書誌情報 |
en : Investigative Ophthalmology & Visual Science
巻 62,
号 3,
p. 27,
発行日 2021-03-18
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| 収録物ID |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
15525783 |
| 出版者 |
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出版者 |
Silverchair |
| 出版者 |
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出版者 |
The Association for Research in Vision and Ophthalmology |
| 権利情報 |
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権利情報 |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
| EID |
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識別子 |
386838 |
| 言語 |
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言語 |
eng |
iovs_62_3_27.pdf (1.31 MB)
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