| Item type |
文献 / Documents(1) |
| 公開日 |
2022-12-21 |
| アクセス権 |
|
|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.31487/j.NNB.2018.10.005 |
|
|
言語 |
ja |
|
|
関連名称 |
10.31487/j.NNB.2018.10.005 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
An increase in corrected QT interval may indicate a good clinical response to amitriptyline in female patients with burning mouth syndrome |
|
言語 |
en |
| タイトル別表記 |
|
|
その他のタイトル |
QTc in burning mouth syndrome |
|
言語 |
en |
| 著者 |
渡邊, 毅
ナガミネ, タカヒコ
ミクヅキ, ルウ
アオタ, ユウマ
スガ, タカユキ
Tu, Trang T.H
タケノシタ, ミホ
トヨフク, アキラ
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Burning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa in the absence of underlying causes. BMS patients can pose a therapeutic challenge to clinicians. Amitriptyline has been a first-line treatment for BMS and is known to prolong corrected QT interval (QTc) in a dose dependent manner. However, little is known about the QTc lengthening effect of amitriptyline at analgesic dosages. The objective of this study was to evaluate changes in QTc in female BMS patients treated with amitriptyline. We conducted a single-center retrospective observational study and evaluated 40 female BMS patients. The QTc interval did not show statistically significant increase with amitriptyline (p=0.1502). However, the change in QTc of amitriptyline-responders was significantly longer than that of non-responders (p=0.0142). The change in QTc may be a non-invasive maker of clinical responses to amitriptyline in female BMS patients. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Amitriptyline |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
autonomic nerve function |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
burning mouth syndrome |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
QTc |
| 書誌情報 |
en : Neurology and Neurobiology
巻 1,
号 1,
発行日 2018-07-22
|
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
26137828 |
| 出版者 |
|
|
出版者 |
Science Repository |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved. |
| EID |
|
|
識別子 |
393255 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
nnb_1_1.pdf (93.6 KB)
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