| Item type |
文献 / Documents(1) |
| 公開日 |
2020-09-02 |
| アクセス権 |
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|
アクセス権 |
open access |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版社版DOI |
|
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3762/bjoc.14.137 |
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|
言語 |
ja |
|
|
関連名称 |
10.3762/bjoc.14.137 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| タイトル |
|
|
タイトル |
Glycosylation reactions mediated by hypervalent iodine : application to the synthesis of nucleosides and carbohydrates |
|
言語 |
en |
| 著者 |
ヨシムラ, ユウイチ
ワカマツ, ヒデアキ
ナトリ, ヨシヒロ
サイトウ, ユカコ
南川, 典昭
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
To synthesize nucleoside and oligosaccharide derivatives, we often use a glycosylation reaction to form a glycoside bond. Coupling reactions between a nucleobase and a sugar donor in the former case, and the reaction between an acceptor and a sugar donor of in the latter are carried out in the presence of an appropriate activator. As an activator of the glycosylation, a combination of a Lewis acid catalyst and a hypervalent iodine was developed for synthesizing 4’-thionucleosides, which could be applied for the synthesis of 4’-selenonucleosides as well. The extension of hypervalent iodine-mediated glycosylation allowed us to couple a nucleobase with cyclic allylsilanes and glycal derivatives to yield carbocyclic nucleosides and 2’,3’-unsaturated nucleosides, respectively. In addition, the combination of hypervalent iodine and Lewis acid could be used for the glycosylation of glycals and thioglycosides to produce disaccharides. In this paper, we review the use of hypervalent iodine-mediated glycosylation reactions for the synthesis of nucleosides and oligosaccharide derivatives. |
|
言語 |
en |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
glycosylation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hypervalent iodine |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Lewis acid |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nucleoside |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
oligosaccharide |
| 書誌情報 |
en : Beilstein Journal of Organic Chemistry
巻 14,
p. 1595-1618,
発行日 2018-06-28
|
| 収録物ID |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
18605397 |
| 出版者 |
|
|
出版者 |
Beilstein-Institut |
|
言語 |
en |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| EID |
|
|
識別子 |
340525 |
|
識別子タイプ |
URI |
| 言語 |
|
|
言語 |
eng |
bjoc_14_1595.pdf (1.33 MB)
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